The London Symphony Orchestra has said it would be keen to play Cypress Hill’s hit Insane In The Brain in a collaboration with the hip hop artists – 21 years after the two groups appeared on an episode of The Simpsons.

The contrasting musical ensembles featured in a 1996 episode of the animated show, in which Homer joins the fictional travelling music festival Hullabalooza and a roadie asks the travelling bands if any of them have hired the London Symphony Orchestra.

In the episode Cypress Hill agreed to hiring the musicians, asking them if they know Insane In The Brain.

More than two decades later Cypress Hill shared a still from the group’s appearance on the show on Twitter alongside the quote from the roadie.

After fans expressed their excitement, the orchestra replied saying “our ‘people’ are talking” and telling another excited music lover: “That Simpsons episode was 20 years ago, so it’s about time!”

When another asked if they would play Insane In The Brain, the orchestra replied: “We mostly know classical but we’ll give it a shot LOL. If this happens, that’ll have to be one of the tracks for sure.”